Default mode network activity in bipolar disorder

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Default mode network abnormalities in bipolar disorder and schizophrenia.

The default-mode network (DMN) consists of a set of brain areas preferentially activated during internally focused tasks. We used functional magnetic resonance imaging (fMRI) to study the DMN in bipolar mania and acute schizophrenia. Participants comprised 17 patients with bipolar disorder (BD), 14 patients with schizophrenia (SZ) and 15 normal controls (NC), who underwent 10-min resting fMRI s...

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Patterns of Default Mode Network Deactivation in Obsessive Compulsive Disorder

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Default mode network subsystem alterations in obsessive-compulsive disorder.

BACKGROUND Although neurobiological models of obsessive-compulsive disorder (OCD) traditionally emphasise the central role of corticostriatal brain regions, studies of default mode network integrity have garnered increasing interest, but have produced conflicting results. AIMS To resolve these discrepant findings by examining the integrity of default mode network subsystems in OCD. METHOD C...

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ژورنال

عنوان ژورنال: Epidemiology and Psychiatric Sciences

سال: 2020

ISSN: 2045-7960,2045-7979

DOI: 10.1017/s2045796020000803